Current Contents

17. Long-term Response: Finite Populations

• Population Genetics of Selection and Drift
  • Drift and selection at a single locus
  • Fixation probabilities for alleles at QTL
  • Expected allele frequency in a particular generation
  • The Cohan effect: increased divergence under uniform selection
  • Results for two loci: the Hill-Robertson effect
• The Efftect of Selection on Effective Population Size
  • The Expected Reduction in N_e from Directional Selection
  • Molecular Variation is Reduced in Regions of Low Recombination
• Drift and Long-term Selection Response
  • Basic Theory
  • Robertson's theory of selection limits
• Tests of Robertson's Theory of Selection Limits
  • Weber's Selection Experiment on Drosphilia Flight Speed
• Effects of Linkage on the Selection Limit
• Optimal Selection Intensities for Maximizing Long-term Response
• Effects of Population Structure on Long-term Response
  • Founder effects and population bottlenecks
  • Population subdivision
  • Within-family selection
• Asymptotic Response due to Mutational Input
  • Results for the infinitesimal model
  • Expected asymptotic response under more general conditions
  • Optimizing Asymptotic Selection Response

PDF versions of a recent draft of this chapter are available. Feel free to use this for personal and/or class use until the book is available. Please note that these are copyrighted and that I would greatly appreciate feedback . Note that while the screen view can look funny in places, the printed output is fine.

• Chapter 17 PDF file ( v. 10 December 1998 ): (55 typeset pages, 825K)

Home Pages: [ Volume One ] - [ Volume Two ] - [ What's new ] - [ Book]

Bruce Walsh. jbwalsh@u.arizona.edu . Comments welcome.