15. The Infinitesimal Model

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15. The Infinitesimal Model

The Infinitesimal Model
Modifications of the Infinitesimal Model
- Gaussian approximations allowing for a finite number of loci and drift
- Linkage: An approximate treatment
- Linkage: A more careful treatment
Response Under Non-Gaussian Distributions
- Describing the genotypic distribution: Moments
- Describing the genotypic distribution: Cumulants and Gram-Charlier series
- Short-term response ignoring linkage effects
- Response when gametic-phase disequilibrium is considered

PDF versions of a recent draft of this chapter are available. Feel free to use this for personal and/or class use until the book is available. Please note that these are copyrighted and that I would greatly appreciate feedback . Note that while the screen view can look funny in places, the printed output is fine.

Chapter 15 PDF file ( v. 14 May 1998 ): (22 typeset pages, 612K)

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Created 16 August 1995, last updated 11 December 2000

Bruce Walsh. jbwalsh@u.arizona.edu . Comments welcome.