1st Volume: Genetics and Analysis of Quantitative Traits

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The authors are Mike Lynch (in the Department of Biology at Indiana University at Bloomington) and myself ( Bruce Walsh in the Department of Ecology and Evolutionary Biology at the University of Arizona).

E-mail the authors.

Expanded Table of Contents


Reviews todate

  1. Warren Ewens, American Journal of Human Biology 11: 798-800. [ review ]
  2. Trudy MacKay, Evolution 53: 307-309. [ review ]
  3. Jim Cheverud, Am. J. Phys. Anthrop. 108: 375-376. [ review ]
  4. J. J. Colleau, Genetics, Selection, Evolution 30: 203-204. [ review ]
  5. Nick Barton, Genetical Research 72: 73. [ review ]
  6. Paul Siegel, Journal of Heredity 90: 256-257. [ review ]
  7. Mary Marazita, Trends in Genetics 15: 120. [ review ]
  8. Outi Savolainen, Forest Genetics 6: 88 [ review ]
  9. William A. Nelson and Elizabeth E. Crone, The Quarterly Review of Biology 74: 225. [review ]
  10. Christopher Basten, Theoretical Population Biology 57: 307 [review ]
  11. Suzanne Leal, American Journal of Human Genetics 68: 548-549. [ review ]
  12. Peter Zhelev, Genetics and Breeding 30 (3-4) 65-66. [ review ]
  13. H. Simianer, J. Animal Breeding and Genetics 119: 406


Current list of typos and other silly errors (last updated 25 August 2003) [ sorted by date error reported ]


Links to web pages, particular programs, and notes/comments on all issues in quantitative genetics (i.e., animal breeding, plant breeding, evolutionary genetics, human genetics) can be found under the appropriate chapters.

Chapters listed in bold have additional notes providing updated material.

Expanded Table of Contents

I. The Genetic Basis of Quantitative Traits

  • 1. An Overview of Quantitative Genetics
  • 2. Properties of Distributions
  • 3. Covariance, Regression, and Correlation
  • 4. Properties of Single Loci
  • 5. Components of Genetic Variation
  • 6. Components of Environmental Variation
  • 7. Resemblance Between Relatives
  • 8. Matrix Algebra and Multiple Regression
  • 9. Analysis of Line Crosses
  • 10. Inbreeding and Outbreeding Depression
  • 11. Matters of Scale
  • II. Quantitative Trait Loci

  • 12. Polygenes and Polygenic Mutation
  • 13. Detecting Major Genes
  • 14. Mapping and Characterizing QTL: Classical Approaches and Basic Concepts of Marker-Based Mapping
  • 15. Mapping and Characterizing QTL: Inbred Line Crosses
  • 16. Mapping and Characterizing QTL: Outbred Populations
  • III. Estimation Procedures

  • 17. Parent-Offspring Regression
  • 18. Sib Analysis
  • 19. Twins and Clones
  • 20. Cross-classified Designs
  • 21. Correlated Characters
  • 22. Genotype X Environment Interaction
  • 23. Maternal Effects
  • 24. Sex-linked Inheritance and Sexual Dimorphism
  • 25. Threshold Characters
  • 26. BLUP Estimation of Genetic Values
  • 27. REML Estimation of Genetic Variances
  • IV. Appendices

  • A1. Methods for Approximating Variances and Covariances
  • A2. Path Analysis
  • A3. Generalized Inverses and Solutions to Singular Systems of Equations
  • A4. Maximum Likelihood Estimation and Likelihood Ratio Tests
  • A5. Computing the Power of Statistical Tests

  • More details:


    Home Pages: [ Volume Two ] - [ What's new ] - [ Book]
    Created 25 February 1995, last updated 24 October 2000

    Bruce Walsh. jbwalsh@ccit.arizona.edu . Comments welcome.