Typos and corrections (sorted by date) 1 March 2006 pg 667, line 3 of first full paragraph. Equation 22.8 should be Equation 22.9 12 December 2003 pg 933 The pages for Risch, N. 1990a Am J Hum Genet 46 should be pp. 222-228 instead of 229-241 25 August 2003 pg 422. Equation 14.22 for the chi-square is incorrect. Simply use the standard expression for a 2 x 2. pg. 843. The chi-square goodness-of-fit statistics in Table A3.1 are, strictly speaking, correct, but totally impractical, as one uses the sum of squared residuals to estimate the residual variance, sigma^2_e. 18 March 2003 pg 32, 2 ln3 above Eq 2.16 (typo) change sigma to sigma^2. 3 Feb 2003 page 448: Pr(chi(1)>4.61)=0.032 (not 0.04 as in the book), so that the 1 LOD drop support is approximately a 97% CI. [ Mangin et al. (1994) may have pointed this out first ] A 2 LOD interval is then a 99.8% CI, since Pr(chi(1)>9.21) = 0.002. 31 January 2002 pg 373, fifth line from bottom: Change "German and German 1984" to "Geman and Geman 1984" pg. 886, Example 5. Pr ( F_(3,16)> 1.215) = 0.337, not 0.103 as given pg. 908 last reference on 1st column: Change "German and German 1984" to "Geman and Geman 1984" pg. 952 3rd column, lines 32, 3: German, D. to Geman, D. and German, S. to Geman, S 15 January 2002 pg. 879, Equation A5.15e. The term in the numerator of the noncentrality parameter should be (mu_i - mubar)^2 instead of mu_i^2. pg. 881, one line above Equation A5.19. The mean of ybar_{i.} should be mu + tau_i, not tau_i (s incorrected given). 2 November 2001 pg 865 2nd line after Eq. A4.22c: interations should be iterations 21 October 2001 pg. 445 Luo and Wolliams 1993 should be Luo and Woolliams 1993. Likewise, change Wolliams to Woolliams on pg. 923 (1st column, 6th ref) and on page 960 (author index). 10 August 2001 pg. 910 The Grossman and Eisen 1989 reference (2nd from the top in column two) is from Journal of Heredity and not from Heredity. 1 July 2001 p. 539, line 16. Instead of "The single offspring-midparent regression..." it should read "The single offspring-midparent CORRELATION...". 9 May 2001 pg. 734, Table 25.1 contains numerous errors, see http://nitro.biosci.arizona.edu/zbook/Table25-1.pdf for a pdf copy of the corrected table 15 January 2001 pg. 568, last paragraph of Example 2 (line 6) : "F_L = F_{19,151,0.025}" should read "F_U = F_{19,151,0.025}"; "F_U = F_{151,19,0.025}" should read "F_L = F_{151,19,0.025}" 13 December 2000 pg. 376, 523, 525, 901: Curtis and Stam should read Curtis and Sham pg. 958: Under Stam, P., the listings for 376, 525, and 525 should be listed under Sham, P. C. 17 October 2000 pg 764 (Example 8), 4th line (ignoring Equations): A55 equals 1.125, not 1.25 as listed. pg 764 (Example 8), For the A matrix at the end of the example, the elements A25 and A52 should be 1/4, not 1/2 as listed. 29 August 2000 pgs. 578-579, Example 3. Several math errors in computing the standard errors. The correct values (using Equation 18.38a) are Var( tPHS ) = 0.00125 (instead of 0.0098) SE( tPHS ) = 0.035 (instead of 0.099) Var( tFS ) = 0.00368 (instead of 0.0127) SE( tFS ) = 0.06 (instead of 0.113) Likewise, using Equation 18.37b, SE( tFS ) = 0.042 (instead of 0.037) 16 May 2000 pg. 96. Equation 8.25c. the covariance matrix should be A V A^T instead of the the (incorrectly) listed value of A^T V A. pg. 546, Equation 17.11a. The denominator should be 4N, not N. 27 March Page 98, Example 3. The SE for Dhat for the Utah population should be 0.020, rather than 0.028 Rufous-collared sparrow (not ruffous): Page 118, 2nd par, line 5; Page 120, line 1; Page 961, column 3 (under Birds); Page 970, 3rd column, last entry 14 March 2000 Page 70, Figure 4.8. the labels on the Y-axis for the case k=0 should go from 0 to 0.5 in 0.1 increments 13 March 2000 Page 73: Example 4 For the case of pB=0.5, the dominance genetic variance component should be 0.0025 (instead of 0.0012) and the total genetic variance thus becomes 0.1765 (instead of 0.1752). Page 74 : last line of the explanation for example 4. Should read "presented in Chapter 14" (Not Chapter 13 as stated) 6 March 2000 pg. 493: Our verbal definition of PIC is incorrect. It should be the probability that the transmission from a (specific) parent can be determined unambiguously. A homozygous child from two identical) heterozygous parents clearly has the paternal/maternal origin of both is alleles unambiguously determined (and hence contributing to PIC). pg. 902, 1st column, ref 3: The correction citation for Demenais et al. 1988 is Annuals of Human Genetics, not Am J. Hum Genet. as listed. 27 February 2000 pg. 310, middle of page. In the definition of phi(y) for character state two, y_c1 should be less than or equal to y, not greater than or equal to y as is written. 10 February 2000 pg. 946: 2nd colum. The page reference for Wright 1921c should be Genetics 6: 124-143 (not 111-123 as is listed) 5 February 2000 pg. 946: The citation for Winer et al (1991) from Appendix 5 is missing. It is: Winer, B. J., D. R. Brown, and K. M. Michels. 1991. Statistical principles in experimental design, 3rd Edition. McGraw-Hill, New York. [A5] pg. 960, first column, line 3: Winder, B. J. should be Winer, B. J. 20 January 2000 pg. 871, 3 lines below Eq. A5.2b. Change "sigma^2" to "sigma^2_1" pg. 882, lines 2 and 3. Change f to F 14 January 2000 pg 23, 5 lines above Eq 2.5: change "E(z^2) - mu" to "E(z^2)- mu^2" pg 40, 2nd line of Figure caption: Change "Table 2.2" to "Table 2.1" pg 40, 2nd line after Equation 3.13c, Change "Equation 3.13b" to "Equation 3.13c" pg 62, line 10: Change "complete dominance of the B_1 allele" to "complete dominance of the B_2 allele" pg 62, line 11: Change "the B_2 allele" to "the B_1 allele" pg 236, 4 lines from bottom. Change "leptokurtic" to "positively skewed" pg 237, line 3 of Example 5: change "Var[ zbar(P1) ] = 0.205 and Var[ zbar(P2) ] = 0.373" to "Var[ zbar(P1) ] = 0.373 and Var[ zbar(P2) ] = 0.205" pg 237, line 4 of Example 5: change "Example 3" to "Example 4" pg 238, last line: change "(alpha^c_{max})/2" to "(alpha^c_{max})^2/2" pg 244, line 5 of first paragraph. Change "consider three approaches" to "consider two approaches" pg 378, line 7: Change "we note than" to "we note that an" pg 426, 2nd line form bottom of third paragraph: Change "used estimate" to "used to estimate" pg 447, 6 lines from bottom: Change "a function of map position" to "a function of the map position" pg 452, 3 lines above Example 6: Change "that, dense" to "that dense" pg 456, 5 lines from bottom (Typo): change "-ln(1-0.76^2) = 14.27" to "-10 ln(1-0.76) = 14.27" pg 457, line 4 (Typo): change "-10 ln(1-0.76^2) / 4.61 = 3.10" to "-10 ln(1-0.76) / 4.61 = 3.10" pg 468 , line 8: Change "-0.0221" to "0.0221" pg 468 , line 26: Change "-0.2407" to "0.2047" pg 811, 2 lines after Equation A.17a: Change "A1.6a" to "A1.6" pg 813, first equation of Example 4: change "beta_n" to "alpha_n" pg 816, 3 lines from bottom: change "optimun" to "optimum" 30 November 1999 pg. 887, 2 line above Eq A5.33a. "sires per dams is given by n = 4/h^4" should read "dams per sire is given by n = 4/h^2" 22 November 1999 pg. 541: Equation 17.5c In the right-most equation, Zo bar_i should simply be Zo_i. 27 Oct. 1999 pg 77, line above Equation 4.23b. This should read "In the former case, it reduces to" (i.e, for randon mating) 24 Sept 1999 pg. 576. Equation 18.36 is in error. The correct version should read F = ( c_dMS_d - c_sMS_s)/MS_e where c_d =( k_2 + k_3)/( k_2 + k_3-k_1) and c_s = k_1 /( k_2 + k_3-k_1) 30 April 1999 pg. 511, Equation 16.30: Strictly speaking, this covariance is conditional on R_ij and hence should read Cov(z_i,z_j | R_ij) 20 April 1999 pg 84, table in Example 1.: the a and k values for P_MM and B_TT were switched, so that the values for P_MM should be a = 21.6, k = 0.06 and for P_TT should be a = 27.0, k = 0.33 20 May 1999 pg 232, 3rd line from bottom: change "number of chromosomes" to haploid number of chromosomes" pg. 897, 1st column, the correct reference for Castle 1921 is Science 54: 223, rather than the PNAS reference given. 16 April 1999 pg. 907, 2nd column, ref 2: "Fulker, Cherry" -- should read "Fulkner, Cherny" 24 March 1999 pg. 448, Equation 15.16 is missing a minus sign, and should read -log_10 2 March 1999 pg 395, 5 lines below Eq. 14.4 . Change e^(-0.2) to e^(-2*0.2) 15 Jan 1999 pg. 721, Table 24.1. The first line in the Male-Male relationships section gives for Father-son a Phi_xy of 1/4, but this should be 0. 14 Jan 1999 pg. 796, Example 4. (i) The two sigma's [the variance components sigma^2_A(k) and sigma^2_E(k)] should have their positions swapped in the vector theta, so that the first (top) element should be sigma^2_E(k) and the second (bottom) element becomes sigma^2_A(k). (ii) The lower left element in the Hessian matrix H should be tr(PPA) - 2yPPAPy, not tr(PAP) - 2yPAPPy as listed 10 Jan 1999 pg. 891 The Amos and Elston 1989 reference is repeated at the bottom of column one and the top of column 2 4 Jan 1999 pg 175, line 2: Change "different" to "differ" 2 December 1998 pg. 499, Equation 16.16. n should be replaced with (n/2). pg. 500, Equation 16.17. [2 corrections] n should be replaced with (n/2) on the left-hand side, and sigma^2_A/4 should be replaced by sigma^2_A/2. 30 November 1998 pg 238, 2nd line after equation in Example 5. Change "n=10" to "n=5.4" 27 October 1998 pg 23, 1 ln about Eq 2.5 (typo) delete "(Example 2, Appendix 1)," pg 45, ln 8 of Example 2: Change "interal" to "interval" page 45: two lines form the bottom: "As noted at the end of last chapter" should read " As noted at the end of the last chapter" 9 November 1998 pg 827, equation in middle of page. Change "G_o = H_p + H_m" to " G_o = H_f + H_m". 12 October 1998 pg. 947: The Wu and Palopoli 1994 reference is from Ann. Rev. Genetics, not Ann. Rev. Ecol. Syst. 27 July 1998 pg. 496, Equation 16.7. The second half of the equation should read Pr(Q_j | M_1) = Pr(Q_i | M_2) = c (Q_j and Q_i were mistakenly reversed) pg. 623. Vertical caption on Figure 20.4 should read "sigma_{P_2,r}(i)" rather than "sigma_{P_2}r(i)". Likewise, "sigma^2_{r(i)}" should instead read "sigma^2_r(i)" pg. 677, Table 22.2. The expected MS for genotype (G) has an extra '+' symbol. pg. 700, 7 lines below Eq. 23.9e. Drop the lead parenthesis before "However" pg. 708, right below Figure 23.5, the phrase "G is the matrix ...and T denotes a transpose" is repeated pg. 888, 3rd line of Example 7 should read "n=25" instead of "N=25" 9 July 1998 pg 814-5. Equation A1.10b n should be (n-1). This results in three other errors. (1) In the second (unnumbered) equation on pg 815, n --> (n-1) (2) In the next line, n [Var(x)]^2/(n+2) --> (n-1) [Var(x)]^2/(n+1) (3) In Equation A1.10c, n+2 --> n+1 (Peter Visscher, Edinburgh, 9 July 1998) 15 June 1998 There is a numbering error in that there is no Table 15.2, so that the table numbering skips from Table 15.1 (page 440) to Table 15.3 (page 479). pg 818, 1st line of Eq. A1.19b. The minus sign on the (mu_n/mu_v^2) term should be deleted. The final result in A1.19b is, however, correct. 8 June 1998 pg 36, line 2: change "p(x) = integral p(y | x) dy" to "p(x) = integral p(y, x) dy" 4 June 1998 There is a numbering error in Chapter 11 in that there is no Table 11.3, so that the table numbering skips from Table 11.2 (page 309) to Table 11.4 (page 315). pg. 425, 4th line of Figure 14.10 caption. change "measured" to "measure" 1 June 1998 pg. 885, Example 4 ln 2: change "n=35" to "n=30", ln 4 : change "lambda = 20*36 " to "lambda = 20*30". 13 May 1998 pg 89, line 3: change "j = U_M" to "l = U_M" 17 April 1998 pg xvi ln 4, pg 498 (3 lines below 16.12), 501 (ln 6), 502 (ln 9), pg 943 (4th ref in column 1),Throughout "van der Beck" should be changed to "van der Beek" . Sorry about that Sijne! 14 April 1998 pg 405, 4th line from bottom. Change "cogenic" to "congenic". 9 April 1998 pg. 561, Equation 18.19. Correction and clarification. Equation 18.19 should read Var(MS) = 2 MS^2/(df + 2). In other words, an ESTIMATE of the true variance of MS [ \sigma^2(MS) ] is approximately given by a function of square of the observed MS. 8 April 1998 pg. 887, 3 lines below Eq A5.33a. "sigma_z =" should read "sigma^2_z" 1 April 1998 pg. 521 In both Equation 16.46a and 15.46b, the (1-2c_{ij}) term should be squared, giving (1-2c_{ij})^2 30 March 1998 pg 138, line -8 (2nd line of last paragraph). Change "female" to "male", so it now reads "Assuming the MALE is the heterogametic sex" pg. 738, 5th line from bottom: Change "from Equation 25.1b" to "from Equation 25.1c" 17 March 1998 pg. 500, last line. The phrase "Combining this" is out of place and should be moved to the top of the page, so that it now reads "Combining this with Equations 16.10b..." pg. 976, 3rd column Under Multiple test significance levels, change the pages "441-444" to "441-442" 19 February 1998 pg 89, 1st equation after header "Dominance Effects". Change P(ijkl | i,j = B_{M}) to P(ijkl | i,j = B_{MM}) [ ie the subscript M should be MM] 2 February 1998 pg. 641, 4 lines from bottom. "see Chapter 14" should read "see Chapter 15" 29 Dec 1997 pg. 861, line 2: "Equation A3.11c" should read "Equation A3.11b" pg. 948 Running title and page number missing from top of page