Volume 2: Evolution and Selection of Quantitative Traits
Bruce Walsh and Michael Lynch
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since 1 March 2009 
Volume 2 is now of sufficient length that it will be published as two separate works.
Draft versions for essentially all of the chapters in Foundations, and many of the chapters in Advanced Topics are given below. The page numbers between chapters are rather random at the moment,
and some are still a bit unpolished in terms of linking material across chapters together.
Preliminary drafts are also posted for a few chapters. These are much rougher but give an idea of the basic topics to be covered.
With these caveats in mind,
please feel free to use these for courses, etc. We simply request your feedback. Please let us know of any errors, omissions, interesting/important papers we missed, etc. Contact us at
jbwalsh@u.arizona.edu .
Don't be bashful about your own work! Once the book does indeed appear, these drafts will be removed from the website.
Note that the chapter numbers listed here reflect the current status of the book, and the actual chapter numbers used in the drafts may differ from these as they may predate some of these changes.
Finally, plesae note that these chapters are copyrighted.
Updates
 26 April 2011: Draft of Chapter 11
(Using Molecular Data To Detect Selection: Signatures from Multiple Historical Events) posted.
 1 April 2011: Draft of Chapter 10
(Using Molecular Data To Detect Selection: Signatures from Recent Single Events
) posted.
 23 March 2011: Draft of Chapter 9
(Using Molecular Data To Detect Selection: Overview) posted.
 1 February 2011: Draft of Appendix 6
(Multiple comparisons: Bonferroni Corrections and False Discovery Rates) posted.
 20 September 2010: Draft of Chapter 27 (Measuring Multivariate Selection) posted.
 13 July 2010: Draft of Chapter 21 (Associative Effects, Competition, Group And Kin Selection) posted.
 2 April 2010: Draft of Chapter 32 (Applications of Index and Multipletrait Selection) posted.
 20 February 2010: Draft of Chapter 15 (ShortTerm Changes In The Variance) posted.
 9 November 2009: Draft of Chapter 19 (Familybased selection) posted.
 3 August 2009: Draft of Chapter 34 (Selection and G x E: Advanced Topics) posted.
 26 July 2009: Draft of Chapter 33 (Selection and G x E: Introduction) posted.
Evolution and Selection of Quantitative Traits: I. Foundations
Total lenght is around 1500 pages, due date: around June 2012. NOTE: Chapters have been reordered several times, so the posted pdf version may have a different chapter number than that listed here.
0. Table of Contents
pdf file of Detailed Table of Contents (version 19 September 2011, 21 pages). Still very rough for Chapter 25 (the currently unwritten chapter). Also, page numbering between chapters is essentially random at this point.
I. Introduction
1. Changes in quantitative characters over time
II. Evolution At One And Two Loci
2. Neutral Evolution In One And TwoLocus Systems
pdf of draft for
Chapter 2. Version: 10 November 2008. 27 pages, 405K.
3. The Genetic Effective Size Of A Population
pdf of draft for
Chapter 3. Version: 30 March 2007. 30 pages, 294K.
4. The Nonadaptive Forces Of Evolution
pdf of draft for
Chapter 4. Version: 24 August 2008. 31 pages, 344K.
5. Changes in Genetic Variance Induced by Random Genetic Drift
pdf of draft for
Chapter 5. Version: 12 September 2008. 40 pages, 475K.
6. The Neutral Divergence of Quantitative Traits
pdf of draft for
Chapter 6. Version: 27 September 2008. 22 pages, 331K.
7. The Population Genetics of Selection
pdf of draft for
Chapter 7. Version: 12 December 2009. 46 pages, 1000K.
8. Interaction of Selection, Mutation, and Drift
pdf of Preliminary draft for
Chapter 8. Version: 2 November 2008. 40 pages, 506K.
9. Using Molecular Data To Detect Selection: Overview
pdf of draft for
Chapter 9. Version: 16 April 2011. 21 pages, 588K.
10. Using Molecular Data To Detect Selection: Signatures from Recent Single Events
pdf of draft for
Chapter 10. Version: 19 April 2011. 99 pages, 1600K.
11. Using Molecular Data To Detect Selection: Signatures from Multiple Historical Events
pdf of draft for
Chapter 11. Version: 26 April 2011. 62 pages, 1087K.
III. ShortTerm Response On A Single Character
12. ShortTerm Changes In The Mean: 1. The Breeders' Equation
pdf of draft for
Chapter 12. Version: 17 November 2008. 38 pages, 944K.
13. ShortTerm Changes In The Mean: 2. Permanent Versus Transient Response
pdf of draft for
Chapter 13. Version: 23 September 2007. 18 pages, 708K.
14. Price's Theorem: A General Equation For Response
pdf of draft for
Chapter 14. Version: 24 September 2008. 20 pages, 660K.
15. ShortTerm Changes In The Variance
pdf of draft for
Chapter 15. Version: 20 February 2010. 37 pages, 880K.
16. Least Squares Analysis Of ShortTerm Selection Experiments
pdf of draft for
Chapter 16. Version: 26 August 2008. 41 pages, 916K.
17. MixedModel And Bayesian Analysis Of Selection Experiments
pdf of draft for
Chapter 17. Version: 13 September 2008. 41 pages, 912K.
18. Environmental Effects and the Response in Natural Populations
pdf of draft for
Chapter 18. Version: 17 October 2008. 30 pages, 764K.
19. FamilyBased Selection
pdf of draft for
Chapter 19. Version: 8 November 2009. 55 pages, 1.1MB.
20. Selection Under Inbreeding
pdf of draft for
Chapter 20. Version: 18 July 2010. 39 pages, 912K.
21. Associative Effects, Competition, Group And Kin Selection
pdf of draft for
Chapter 21. Version: 13 July 2010. 60 pages, 1.0MB.
VI. PopulationGenetic Models of Trait Response
22. The Infinitesimal Model and its extensions
pdf of draft for
Chapter 22. Version: 18 July 2008. 34 pages, 940K.
23. LongTerm Response: Deterministic Aspects
pdf of Preliminary draft for
Chapter 23. Version: 13 October 2008. 31 pages, 884. K
24. LongTerm Response: Finite Populations
pdf of Preliminary draft for
Chapter 24. Version: 7 October 2008. 50 pages, 1MB.
25. Maintenance Of Quantitative Genetic Variability
V. Measuring Selection
26. Individual Fitness And The Measurement Of Univariate Selection
pdf of draft for
Chapter 26. Version: 14 November 2008. 40 pages, 964K.
27. Measuring Multivariate Selection
pdf of draft for
Chapter 27. Version: 10 September 2010. 44 pages, 1MB.
VI. Selection On Multiple Characters
28. Multivariate Response: Changes In Means
pdf of draft for
Chapter 28. Version: 25 December 2008. 44 pages, 1MB.
29. Multivariate Response: Changes In Covariances
pdf of draft for
Chapter 29. Version: 23 Jan 2009. 43 pages, 968K.
30. Comparisons of G and its Stability
pdf of draft for
Chapter 30. Version: 28 Jan 2009. 47 pages, 960K.
31. Theory Of Index Selection
pdf of draft for
Chapter 31. Version: 6 December 2008. 54 pages, 1MB.
32. Applications of Index and Multipletrait Selection
pdf of draft for
Chapter 32. Version: 2 April 2010. 54 pages, 884K
33. Selection and G x E: Introduction
pdf of draft for
Chapter 33. Version: 26 July 2009. 28 pages, 740K.
34. Selection and G x E: Advanced Topics
pdf of draft for
Chapter 34. Version: 3 August 2009. 58 pages, 1MB.
VII. Appendices
A1. Diffusion Theory
pdf of draft for
Appendix 1. Version: 18 August 2008. 19 pages, 696 K.
A2. Introduction To Bayesian Statistics
pdf of draft for
Appendix 2. Version: 23 April 2009. 18 pages, 764K.
A3. MCMC Methods And Bayesian Analysis
pdf of draft for
Appendix 3. Version: 12 September 2008. 19 pages, 784K.
A4. The Geometry Of Vectors And Matrices: Eigenvalues And Eigenvectors
pdf of draft for
Appendix 4. Version: 18 November 2008. 19 pages, 776 K.
A5. Derivatives Of Vectors And VectorValued Functions
pdf of draft for
Appendix 5. Version: 7 October 2008. 10 pages, 584 K.
A6. Multiple comparisons: Bonferroni Corrections and False Discovery Rates
pdf of draft for
Appendix 6. Version: 1 February 2011 14 pages, 580 K.
Evolution and Selection of Quantitative Traits: II. Advanced Topics in Breeding and Evolution
0. Table of Contents
pdf file of Detailed Table of Contents (version 28 October 2010, 6 pages). Still very rough for unfinished/not yet written chapters. Also, page numbering between
chapters is essentially random.
VIII. ShortTerm Response On A Single Character: Advanced Topics
35. Selection And Development Of Pure Lines
pdf of Preliminary draft for
Chapter 35. Version: 21 Feb 2009. 43 pages, 788K.
36. Selection And Crossbreeding I. Basic Concepts
pdf of Preliminary draft for
Chapter 36. Version: 21 Feb 2009. 42 pages, 908K.
37. Selection And Crossbreeding II. Advanced Topics
pdf of VERY rough preliminary draft for
Chapter 37. Version: 3 April 2002. 32 pages, 760K.
38. Selection In AgeStructured Populations
IX. Selection On Multiple Characters
39. BLUP Selection
40. MarkerAssisted and Genomic Selection
41. MultipleTrait Models of Maternal and Associate Effects
X. Quantitative Genetics Of Continuous Functions
42. Estimation; Random Regressions And InfiniteDimensional Trait
43. Selection On Functions
XI. Phenotypic Evolution Models
44. Ecological Applications
45. Sexual Selection
46. Macroevolution
XII. Development and adaptation
47. Evolution and development
48. Networks and pathways
49. Summary: the nature of adaptation
Created 1 March 2009, last updated 15 May 2011
Bruce Walsh. jbwalsh@u.arizona.edu .
Comments welcome.