Volume 2: Evolution and Selection of Quantitative Traits

Bruce Walsh and Michael Lynch

 You are visitor number   since 1 March 2009 

Volume 2 is now of sufficient length that it will be published as two separate works. pdf of draft for Chapter 2.

Draft versions for essentially all of the chapters in Foundations, and many of the chapters in Advanced Topics are given below. The page numbers between chapters are rather random at the moment, and some are still a bit unpolished in terms of linking material across chapters together. Preliminary drafts are also posted for a few chapters. These are much rougher but give an idea of the basic topics to be covered.

With these caveats in mind, please feel free to use these for courses, etc. We simply request your feedback. Please let us know of any errors, omissions, interesting/important papers we missed, etc. Contact us at jbwalsh@u.arizona.edu . Don't be bashful about your own work! Once the book does indeed appear, these drafts will be removed from the website.

Note that the chapter numbers listed here reflect the current status of the book, and the actual chapter numbers used in the drafts may differ from these as they may predate some of these changes.

Finally, plesae note that these chapters are copyrighted.


Evolution and Selection of Quantitative Traits: I. Foundations

Total lenght is around 1300 pages. NOTE: Chapters have been reordered several times, so the posted pdf version may have a different chapter number than that listed here.

0. Table of Contents

  • pdf file of Detailed Table of Contents (version 30 December 2014). Still very rough for Chapter 27 (the remaining unwritten chapter). Also, page numbering between chapters is essentially random at this point.
  • I. Introduction

  • 1. Changes in quantitative characters over time

  • II. Evolution At One And Two Loci

  • 2. Neutral Evolution In One- And Two-Locus Systems

  • 3. The Genetic Effective Size Of A Population

  • 4. The Nonadaptive Forces Of Evolution

  • 5. The Population Genetics of Selection

  • 6. Theorems of Natural Selection: Results of Price, Fisher, and Robertson

  • 7. Interaction of Selection, Mutation, and Drift

  • 8. Hitchhiking and Selective Sweeps

  • 9. Using Molecular Data To Detect Selection: Signatures from Recent Single Events

  • 10. Using Molecular Data To Detect Selection: Signatures from Multiple Historical Events

  • III. Drift and Quantitative Traits

  • 11 Changes in Genetic Variance Induced by Random Genetic Drift

  • 12. The Neutral Divergence of Quantitative Traits

  • IV. Short-Term Response On A Single Character

  • 13. Short-Term Changes In The Mean: 1. The Breeders' Equation

  • 14. Short-Term Changes In The Mean: 2. Truncation and Threshold Selection

  • 15. Short-Term Changes In The Mean: 3. Permanent Versus Transient Response

  • 16. Short-Term Changes In The Variance. 1. Changes in the Additive Variance

  • 17. Short-Term Changes In The Variance. 2. Changes in the Environmental Variance

  • 18. Least Squares Analysis Of Short-Term Selection Experiments

  • 19. Mixed-Model And Bayesian Analysis Of Selection Experiments

  • 20. Environmental Effects and the Response in Natural Populations

  • V. Response in Structured Populations

  • 21. Family-Based Selection

  • 22. Associative Effects, Competition, Group And Kin Selection

  • 23 Selection Under Inbreeding

  • VI. Population-Genetic Models of Trait Response

  • 24. The Infinitesimal Model and its extensions

  • 25. Long-Term Response: Deterministic Aspects

  • 26. Long-Term Response: Finite Populations

  • 27. Maintenance Of Quantitative Genetic Variability

  • VII. Measuring Selection

  • 28. Individual Fitness And The Measurement Of Univariate Selection

  • 29. Measuring Multivariate Selection

  • VIII. Appendices

  • A1. Diffusion Theory

  • A2. Introduction To Bayesian Statistics

  • A3. MCMC Methods And Bayesian Analysis

  • A4. Multiple comparisons: Bonferroni Corrections and False Discovery Rates

  • A5. The Geometry Of Vectors And Matrices: Eigenvalues And Eigenvectors

  • Evolution and Selection of Quantitative Traits: II. Advanced Topics in Breeding and Evolution

    0. Table of Contents

  • pdf file of Detailed Table of Contents (version 5 April 2013, 8 pages). Still very rough for unfinished/not yet written chapters. Also, page numbering between chapters is essentially random.
  • IX. Short-Term Response On A Single Character: Advanced Topics

  • 30. Selection And Development Of Pure Lines

  • 31. Selection And Crossbreeding I. Basic Concepts

  • 32. Selection And Crossbreeding II. Advanced Topics

  • 33. Selection In Age-Structured Populations

  • X. Selection On Multiple Characters : Theory

  • 34. Multivariate Response: Changes In Means

  • 35. Multivariate Response: Changes In Covariances

  • 36. Comparisons of G and its Stability

  • 37. Theory Of Index Selection

  • XI. Selection On Multiple Characters : Applications

  • 38. Applications of Index Selection

  • 39. BLUP Selection

  • 40. Marker-Assisted and Genomic Selection

  • 41. Multiple-Trait Models of Maternal and Associate Effects

  • 42. Phenotypic Evolution Models

  • XII. Selection and G x E

  • 43. Selection and G x E: Introduction

  • 44. Selection and G x E: Advanced Topics
  • XIII. Quantitative Genetics Of Continuous Functions

  • 45. Random Regressions And Infinite-Dimensional Trait

  • XI. Appendices

  • A6. Derivatives of Vectors and Vector-valued Functions

  • Created 1 March 2009, last updated 15 May 2011

    Bruce Walsh. jbwalsh@u.arizona.edu . Comments welcome.