Synbreed 2013 Summer School:

Selection and Response on Quantitative Traits

Munich, 1 - 12 July 2013

INSTRUCTOR:

Bruce Walsh, Department of Ecology & Evolutionary Biology, University of Arizona. jbwalsh@u.arizona.edu

Goals: An extensive treatment of the modern theory of selection and selection response with a focus towards applications in plant and animal breeding.

References

LECTURE SCHEDULE

Additional/background reading listed under each lecture

Monday 1 July: Stats Review

1: Basic Stats

2: Linear Algebra

3: Linear Models

4: Bayesian Statistics/MCMC methods

Tuesday 2 July: Quantitative Genetics Review

5: Introduction to Quantitative Genetics

6: Resemblance between relatives 7: Inbreeding and heterosis 8: Mixed-Model estimation (BLUP/REML)

Wes. 3 July: Basic Univariate Selection

9: Basic mass selection

10: Short-term changes in Variances (Bulmer effect) 11: Selection on the environmental variance 12: Mixed model and Bayesian analysis of selection experiments

Thur 4 July: Advanced Univariate Response

13: Family-based selection

14: Selection with inbreeding 15: Development of pure lines 16: Maternal effects

Friday 5 July: Population Genetics of selection

17: Associative effects

18: Basic Pop genetics of selection 19: Selective Sweeps and Hitchhiking 20: Detecting selection with molecular markers

Monday 8 July:, review of previous material

21: Infinitesimal model

22: Long-term selection:

Tuesday 9 July Multivariate selection

23: Multivariate breeder's equation

24: Changes in G 25: Index selection I: theory

Wes 10 July: Index selection

26: Index selection 2: Applications 1

27: Index selection 3: Applications 2 28: BLUP selection/Genomic selection

Thursday 11 July: Advanced topics

29: Stability and Dimension of the G matrix

30: G x E: Introduction 31: G x E: selection response 32: Random Regressions

Friday 12 July: final discussion