EEB 461/561		Molecular Evolution
Time and room:  	Tu/Th 9:30-10:45	@ S Sci 114
Course   WWW page:  http://nitro.biosci.arizona.edu/zeeb/courses/EEB461/eeb461.html

Course Instructors

Bruce Walsh 	LSS 327A  	Nancy Moran	BSW 327
Office hours: 	Mon 8:30-9:30	Office hours:	Wednesday 3-5	
Office phone:	621-1915	Office phone:	621-3581
e-mail:         jbwalsh@ccit.arizona.edu	e-mail:       moran@ccit.arizona.edu	


Michael Hammer	BSW 246				Martin Taylor    Marley 641A
Office hours:	Wednesday 9-11			Office hours:	
Office phone:	621-9828				Office phone:   621-5346
e-mail:	hammer@brahams.arizona.edu	e-mail:     taylor@ccit.arizona.edu		

	Readings
24-Aug	The Neutral theory	Walsh	Chapter 2
29-Aug	The Neutral theory	Walsh	Chapter 2
31-Aug	The Neutral theory	Walsh	Chapter 2
5-Sep	Rates & patterns of  sequence evolution	Walsh	Chapter 3
7-Sep	Rates & patterns of   sequence evolution	Walsh	Chapter 4
12-Sep	TEST ONE		
14-Sep	tests of selection	Taylor	
26-Sep	tests of selection	Taylor	
28-Sep	tests of selection	Taylor	
3-Oct	sequence alignment	Taylor	
5-Oct	Molecular phylogeny	Moran	pp 99-119
10-Oct	Molecular phylogeny	Moran	pp 99-119	
12-Oct	Molecular phylogeny	Moran	pp 99-119	
17-Oct	Codon useage and base composition	Moran	pp 219-221 
19-Oct	More on codon useage  	Moran	pp 219-221	
24-Oct	origins of organelles	Moran	pp 126-128
26-Oct	TEST TWO	 	
31-Oct	Phylogeny of Human and Apes	Hammer	pp. 119-125
2-Nov	Intraspecific Phylogeny I	Hammer	
7-Nov	mtDNA and Y chromosome evolution	Hammer	
8-Nov	Intraspecific Phylogeny II	Hammer	
14-Nov	Evolution of new gene   function	Walsh	Chapter 6
16-Nov	mobile genetic elements	Walsh	Chapter 7
21-Nov	student presentations		
23-Nov	student presentations		
28-Nov	Thanksgiving!		
30-Nov	student presentations		
5-Dec	student presentations		
7-Dec	student presentations

Grading:  points breakdown				 
Exams (one and two)	40%	faculty grading of presentations	      20%  
quizes			30%	student grading of presentations      10%