Home page for Genetics 320

"Even the dogs may eat the crumbs which fall from the rich man's table; and in these days, when the rich in knowledge eat such specialised food at such separate tables, only the dogs have a chance of a balanced diet." ascribed to Sir Geoffrey Vickers

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 since 10 August 2001 

Lecture Schedule and homework due dates == // == Honors == // == Announcements == // == Grade postings and Family Educational Rights and Privacy Act == // == Grading and course policy == // == General course information == // == Instructors == // == TAs == // == Study Groups

Lecture Notes == / == Grade tracker == // == Problem Sets == // == Exams == // == Class handouts == // == Old Exams

Terms students are expected to know from previous courses.

Other Home pages: EEB --//-- MCB --//-- Biochem --//-- U of A Genetics Graduate program --//-- BLC --//-- UBRP

Announcements

All grades are now posted Grade tracker

Final:


Genetics Job!

Seeking an undergraduate lab assistant to work on a project in human population genetics. A qualified student will be trained in basic DNA laboratory skills (e.g. PCR, DNA sequencing, RFLP etc.) and will assist a PhD student in generating data towards publication in professional journals. No prior lab experience required, but must have a strong interest in genetics. Sophmores and Juniors are preferred. Underrepresented minority students are strongly encouraged to apply.

Contact Matt Saunders by e-mail: msaunder@u.arizona.edu

Problem set 11, which covers additional material on the final (but does not need to be turned in), is now posted, and solutions will be posted next week. Solutions.

Ted Weinert's Webpage. Note that lecture note and problem set links are intergrated below.

Study Groups

  • If you wish to form a study group, send me an e-mail and I'll post a listing of interested parties.

    Problem Sets

    Problem sets can be picked up on the wall organizer outside of BSW 211.

    1. Problem set One (Due 31 August)

    2. Problem set Two (Due 7 September)

    3. Problem set Three (Due 21 September)

    4. Problem set Four

    5. Problem set Five

    6. Problem set Six

    7. Problem set Seven

    8. Problem set Eight (Due Friday, 16 Nov)

    9. Problem set Nine (Due Wednesday, 21 Nov)

    10. Problem set Ten (Due Friday, 30 Nov)

    11. Problem set Eleven (Problems for the final, not for turning in)


    Additonal Problem

    1. Extra problems (from Ted) on Epistasis.

    Lecture Notes

    Monday 20 August Lecture 1 The Human Genome Project
    Wednesday 22 August Lecture 2 Basic Probability theory useful in Genetics
    Friday (AM) 24 August Lectures 3 and 4 Mendelian analysis
    Friday (PM) 24 August Lectures 3 and 4 Mendelian analysis
    Monday 27 August Lecture 5 Chromosomal Theory of Heredity
    Wednesday 29 August Lecture 6 Extensions of Mendelian analysis
    Friday (AM) 31 August Lectures 7 and 8 Sex: Chromosomes, Determination, and Linkage
    Friday (PM) 31 August Lectures 7 and 8 Sex: Chromosomes, Determination, and Linkage , review PS 1
    Monday 3 September Labor day: Holiday
    Wednesday 5 September Lecture 9 Genetics of Color Vision
    Friday (AM) 7 September Lecture 10 Understanding Biology by using Genetics
    Friday (PM) 7 September Lectures 11-15 The Lac Operon
    Monday 10 September Lectures 11-15 The Lac Operon
    Wednesday 12 September Lectures 11-15 The Lac Operon
    Friday (AM) 14 September Lectures 11-15 The Lac Operon
    Friday (PM) 14 September Lectures 11-15 The Lac Operon
    Monday 17 September Lecture 16 SOS Operon
    Wednesday 19 September Lecture 17
    Friday (AM) 21 September Lecture 18
    Friday (PM) 21 September Lecture 19
    Monday 24 September Lecture 20
    Wednesday 26 September Review for Exam one
    Friday 28 September EXAM ONE
    Monday 1 October Lectures 21-22 Recombination in Bacteria
    Wednesday 3 October Lectures 21-22 Recombination in Bacteria
    Friday 5 October Lecture 23 Genetic Tests of Genetic Code
    Friday 5 October (PM) Lecture 24
    Monday 8 October Lecture 25
    Wednesday 10 October Lecture 26
    Friday 12 October Lecture 27
    Friday 12 October (PM) Lecture 28
    Monday 15 October Lecture 29 Yeast Genetics
    Wednesday 17 October Lecture 30
    Friday 19 October (AM) Lecture 31
    Friday 19 October (PM) Lecture 32 Yeast Mating Pathway
    Monday 22 October Lecture 33
    Wednesday 24 October Lecture 34
    Friday 26 October (AM) Lecture 35
    Friday 26 October (PM) Lecture 36
    Monday 29 October Lecture 37 Cancer Genetics
    Wednesday 31 October Review for Exam 2
    Friday 2 November EXAM TWO
    Monday 5 November
    Wednesday 7 November Lecture 39 Linkage
    Friday (AM) 9 November Lectures 40 and 41 3 -point test cross
    Friday (PM) 9 November Lectures 40 and 41 3 -point test cross
    Monday 12 November Holiday: Veteran's day
    Wednesday 14 November Lecture 42 Mapping QTLs and Disease genes
    Friday (AM) 19 November Lecture 43 Changes in Chromosome Structure
    Friday (PM) 19 November Lecture 44 Review Problem set
    Monday 19 November Lecture 45 Changes in Chromosome Number
    Wednesday 21 November Lecture 46 Population Genetics I: Variation, Hardy-Weinberg, and Linkage Disequilibrium
    Friday 23 November Thanksgiving Holiday
    Monday 26 November Lecture 47 Population Genetics II: Mutation, Inbreeding, and Genetic Drift
    Wednesday 28 November Lecture 48 Population Genetics III: Natural Selection
    Friday 30 (AM) November Lecture 49 Population Genetics VI: Interaction of Selection and Drift
    Friday 30 (AM) November Lecture 50 The Neutral Theory of Molecular Evolution
    Monday 3 December EXAM THREE
    Wednesday 5 December Review Problem sets, final
    Wednesday 12 December; 11 AM CBS 204 FINAL

    Class handouts

    Old class handouts can be picked up outside of BSW 211 for up to about a week after they were issued. All handouts are posted here, but in pdf (Adobe Acrobat) format. Many browsers have plugs-ins to read such files. Hence, if you are more than one week late in picking up old handouts, its up to you to find a pdf browser. Good luck!!

    General Course Information

    Lecture Time and Place: M,W,F 11am 204 CBS (KOFFL bldg); F. 2pm Modern Lang 350

    Reading Material: An Introduction to Genetic Analysis (7th Edition) by Griffiths et al. is required. The Student Companion to Genetic Analysis, which gives detailed answers to the book problems is optional, but students have found it very helpful. Extra readings may be assigned and these will be put on reserve in Main Library.

    Grade postings and Family Educational Rights and Privacy Act

    It is a violation of the federal Family Educational Rights and Privacy Act (FERPA) to publicly post student grades that are identified by the student's name, institutional student identification number, or social security number without first having obtained the student's written permission. This regulation applies to Web sites and grade sheets left with office staff as well as to the more traditional posting sites such as bulletin boards and office doors.

    Accordingly, attached to the first homework assignment will be a form for you to sign if you wish to have your scores for homework, tests, etc. posted (on the website and class bulletin boards). The method of posting with the the last four digits of your SS number. Not signing this form has absolutely no effect on your grade, and it is completely voluntary.

    If you do not sign this form, to ensure your privacy, I will only give out your scores if you visit me during office hours, after showing me a picture ID. To protect your privacy, no scores will be given over the phone or e-mail (unless you have signed the posting consent form).

    Grading and Course Policy

    Problem sets: Problem sets must be handed in at the start of the 11 am Fri. class (unless otherwise noted in the syllabus). Problem sets handed in late will receive zero credit.

    In the very rare event that you have to miss class on Friday, you can also fax in your problem sets (621-9190), but to receive any credit:

    Individuals who do not turn in either of the first two problem sets can be dropped from the course without notice

    Exams: There are three 100 point midterms (Friday, 28 September; Friday, 2 November; Monday, 3 December) and a 200 point final (Wednesday, 12 December). Material for exams will come from readings, problem sets, and lectures.

    Grading: Material for exams will come from readings and lecture. Problem sets must handed in at the start of the 11 am Fri. class (unless otherwise noted on the syllabus) on dates indicated. Problem sets handed in late receive zero credit.

    Material Points
    Lecture exam 1 100
    Lecture exam 2 100
    Lecture exam 3 100
    12 lecture problem sets 120
    Final Exam 200

    Your final grade will be computed two different ways, and you will receive the HIGHER of the two. One method uses the percentage of the total highest score, with 90% (and up) of the highest total score = A, 80-89% = B, 70-79% = C, 60-69% = D. (If you are worried, we round up from the nearest 0.5, so that 89.500 = 90, but 89.499 = 89). The advantage of using the total percentage is that (in theory) the entire class can get an A. The second method uses normal (z) scores, which depend on the overall distribution of test scores. The advantage of using z-scores is that very good (or very bad) exam performances are more highly weighted. You can track your current grade status via your SS number using the Grade tracker .

    Regrading: Request for regrading of any material (exam or problem set) must be made in writing to the grader using a special form (available from Dr. Walsh or the grader) within 1 week of receiving the grade. The complete exam or problem set may be regraded, and a higher or lower score may result.

    Class policy on missed exams: Attendance is required for lecture and problem solving sessions. The Friday 2 p.m. meeting is mandatory. Students will receive no credit, a zero, for problem sets and exams that are missed. NO MAKE UP EXAMS OR PROBLEM SETS WILL BE GIVEN.

    Procedure to Resolve Disputes: First see grader; then Dr. Walsh

    Class policy on study groups: You are encouraged to form study groups to discuss lecture material and problems sets. If you study and discuss problem sets in a study group put the names of all members of your study group on the first page of your answers. You will NOT be penalized for this. HOWEVER, DO NOT COPY ANSWERS FROM EACH OTHER. Discuss the problems in your study group and then go home and write up your answers alone.

    Class policy on "academic integrity": Your academic work (exams and problem sets) must be your own; do not copy answers to problem sets or anything else; cheating and plagiarism will not be tolerated on exams or problem sets. If you are caught, any combination of the following will occur (UA Code of Academic Integrity): a zero grade will be assigned for the work; course grade dropped one letter grade; course grade of F; disciplinary probation from University; suspension from the University; notation "Declared guilty of violation of the Code of Academic Integrity" put on student's permanent record.

    Honors

    Instructors

    Exams

    1. Exam One

    2. Exam Two
    3. Exam Three

    Previous Exams