READ (in the designated order):

1. Sehgal et al. (1994). Loss of circadian behavioral rhythms and per RNA oscillations in the Drosophila mutant timeless. Science 263:1603-1606.

2. Curtin et al. (1995). Temporally regulated nuclear entry of the Drosophila period protein contributes to the circadian clock. Neuron 14:365-372.

WRITE (for each paper):

1. The MAIN conclusion(s) of that paper (NOT of previous papers). Do not include a detailed summary of everything in the paper (although you may want to keep such notes for yourself).

2. Questions that are raised by the new findings.

Note:

• Bring copies of the papers with you to class.
• If you handwrite your assignment, make sure your writing is legible.
• Don't quote the article--answer the questions in your own words.
• Keep a copy of your written assignment for yourself so you can refer to it in class.
• Think about whether the conclusion promised by the title of the paper is well supported by the experimental data.