Home page for Genetics 320

"Even the dogs may eat the crumbs which fall from the rich man's table; and in these days, when the rich in knowledge eat such specialised food at such separate tables, only the dogs have a chance of a balanced diet." ascribed to Sir Geoffrey Vickers

 You are visitor number 
 since 1 June 1999 

Lecture Schedule and homework due dates == // == Honors == // == Announcements == // == Grade postings and Family Educational Rights and Privacy Act == // == Grading and course policy == // == General course information == // == Instructors == // == TAs == // == Study Groups

Lecture Notes == / == Grade tracker == // == Problem Sets == // == Exams == // == Class handouts == // == Old Exams

Terms students are expected to know from previous courses.

Other Home pages: EEB --//-- MCB --//-- Biochem --//-- U of A Genetics Graduate program --//-- BLC --//-- UBRP --//-- Register here for a U of A e-mail account

A copy of the course text (Griffiths, A., et. al., An introduction to genetic analysis) is now on reserve. The call number is YMRP 213

Announcements

Final grades posted on Grade tracker

Final exams can be picked up in the boxed outside of BSW 211 (where the homework is usually found).

Key for Final

Final Exam Curve

Study Groups

  • If you wish to form a study group, send me an e-mail and I'll post a listing of interested parties.

    Problem Sets

    Problem sets and their solutions are posted as pdf (adobe acrobat files). Most recent browsers launch these files directly, but some of you with older browsers will have to search the net for the free pdf reader for your particular system. Note that the screen output from some pdf files can look rather odd, but they print up just fine.

    Optional problems

    1. Problems in probability. --- Solutions
    2. Selection -- solution
    3. Quantitative Genetics -- Solutions

    Problem Sets

    1. Problem set One (Due 3 Sept 1999)

    2. Problem set Two (Due 10 Sept 1999)

    3. Problem set Three (Due 17 Sept 1999)

    4. Problem set Four (Due 24 Sept 1999)

    5. Problem set Five (Due 29 Sept 1999)

    6. Problem set Six (Due 8 Oct 1999)

    7. Problem set Seven (Due 15 Oct 1999)

    8. Problem set Eight (Due 22 Oct 1999)

    9. Problem set Nine (Due 3 Nov 1999)

    10. Problem set Ten (Due 19 Nov 1999)

    11. Problem set Eleven (Due Wednesday Nov 24 1999)

    12. Problem set Twelve (Due Wednesday 8 Dec. 1999)

    Summary for total homework points

    Lecture Notes

    Monday 23 August Lecture 1 Introduction to Probability theory 1
    Wednesday 25 August Lecture 2 Introduction to Probability theory 2: distributions
    Friday (AM) 27 August Lectures 3/4 Mendelian analysis 1
    Monday 30 August Lecture 5 Chromosomal Theory of Heredity
    Wednesday 1 September Lecture 6 Extensions of Mendelian analysis
    Friday 3 September Lectures 7 and 8 Sex: Chromosomes, Determination, and Linkage
    Monday 6 September Labor day: Holiday
    Wednesday 8 September Lecture 9 Genetics of Color Vision
    Friday 10 September Lectures 10 and 11 Linkage I and II
    Monday 13 September Lecture 12 3-point test cross
    Wednesday 15 September Lecture 13 Genetic maps and mapping functions
    Friday 17 September Lectures 14 and 15 Mapping disease genes
    Monday 20 September Lecture 16 Fungal Genetics
    Wednesday 22 September Lecture 17 Mutation
    Friday 24 September Lectures 18 and 19 Changes in Chromosome Structure
    Monday 27 September Lecture 20 Changes in Chromosome Number
    Wednesday 29 September Review for Exam one
    Friday 1 October EXAM ONE
    Monday 4 October Lecture 21 Human genetic disease
    Wednesday 6 October Lectures 22 and 23 Cloning human disease genes I
    Friday 8 October Lectures 22 and 23 Cloning human disease genes II
    Friday 8 October (PM) Review Problem Set
    Monday 11 October Lecture 25 Using cloned genes for disease screening
    Wednesday 13 October Lecture 26 Using cloned genes for gene therapy
    Friday 15 October Lecture 27 Using cloned genes to understand molecular defects
    Friday 15 October (PM) Review Problem Set
    Monday 18 October Lecture 29 Using mice as a model organism
    Wednesday 20 October Lecture 30 Using flies as a model organism
    Friday 22 October (AM) Lectures 31 and 32 Using worms as a model organism
    Monday 25 October Lecture 33 Using yeast as a model organism
    Wednesday 27 October Lecture 34 Designing mutant hunts
    Friday 29 October (AM) Lectures 35 and 36 Mutant analysis I
    Monday 1 November Lecture 37 Mutant analysis II
    Wednesday 3 November Review for Exam 2
    Friday 5 November EXAM TWO
    Monday 8 November Lecture 38 Extranuclear inheritance
    Wednesday 10 November Lectures 39 and 40 Recombination and Gene Conversion II
    Friday 12 November Lectures 39 and 40 Recombination and Gene Conversion II
    Monday 15 November Lecture 41 Population Genetics I: Variation, Hardy-Weinberg and Linkage Disequilibrium
    Wednesday 17 November Lecture 42 Population Genetics II: Mutation, Inbreeding, and Genetic Drift
    Friday 19 November Lecture 43 Population Genetics III: Natural selection
    Monday 22 November Lecture 44 Population Genetics IV: Interaction of Selection with Mutation and Drift
    Wednesday 24 November Lecture 45 Molecular Evolution and the Neutral Theory
    Friday 26 November Thanksgiving Holiday
    Monday 29 November Lecture 46 Quantitative Genetics I: Basic statistical issues
    Wednesday 1 December Lecture 47 Quantitative Genetics II: Resemblance between relatives
    Friday 3 December Lecture 48 Quantitative Genetics III: Evolution and Selection Response
    Monday 6 December EXAM THREE
    Wednesday 8 December Review for Final
    Wednesday 15 December; 11 AM CBS 204 FINAL

    Class handouts

    Old class handouts can be picked up outside of BSW 211 for up to about a week after they were issued. All handouts are posted here, but in pdf (Adobe Acrobat) format. Many browsers have plugs-ins to read such files. Hence, if you are more than one week late in picking up old handouts, its up to you to find a pdf browser. Good luck!!

    Note that some pdf files look funny on the screen (equations often don't align), but they print out fine.

    Problem sets and their solutions.

    General Course Information

    Lecture Time and Place: M,W,F 11am 204 CBS; F. 2pm 100 BSE

    Reading Material: Genetic Analysis (6th Edition) by Griffiths et al. is required. The Student Companion to Genetic Analysis, which gives detailed answers to the book problems is optional, but students have found it very helpful. Extra readings may be assigned and these will be put on reserve in Main Library.

    Grade postings and Family Educational Rights and Privacy Act

    It is a violation of the federal Family Educational Rights and Privacy Act (FERPA) to publicly post student grades that are identified by the student's name, institutional student identification number, or social security number without first having obtained the student's written permission. This regulation applies to Web sites and grade sheets left with office staff as well as to the more traditional posting sites such as bulletin boards and office doors.

    Accordingly, attacked to the first homework assignment will be a form for you to sign if you wish to have your scores for homework, tests, etc. posted (on the website and class bulletin boards). The method of posting with the the last four digits of your SS number. Not signing this form has absolutely no effect on your grade, and it is completely voluntary.

    If you do not sign this form, to ensure your privacy, I will only give out your scores if you visit me during office hours, after showing me a picture ID. To protect your privacy, no scores will be given over the phone or e-mail (unless you have signed the posting consent form).

    Grading and Course Policy

    Problem sets: Problem sets must handed in at the start of the 11 am Fri. class (unless otherwise noted in the syllabus). Problem sets handed in late will receive zero credit.

    In the very rare event that you have to miss class on Friday, you can also fax in your problem sets (621-9190), but to receive any credit:

    Individuals who do not turn in either of the first two problem sets can be dropped from the course without notice

    Exams: There are three 100 point midterms (Friday, 1 October; Friday, 5 November; Monday, 6 December) and a 200 point final (Wednesday, 15 December). Material for exams will come from readings, problem sets, and lectures.

    Grading: Material for exams will come from readings and lecture. Problem sets must handed in at the start of the 11 am Fri. class (unless otherwise noted on the syllabus) on dates indicated. Problem sets handed in late receive zero credit.

    Material Points
    Lecture exam 1 100
    Lecture exam 2 100
    Lecture exam 3 100
    12 lecture problem sets 120
    Final Exam 200

    Your final grade will be computed two different ways, and you will receive the HIGHER of the two. One method uses the percentage of the total highest score, with 90% (and up) of the highest total score = A, 80-89% = B, 70-79% = C, 60-69% = D. (If you are worried, we round up from the nearest 0.5, so that 89.500 = 90, but 89.499 = 89). The advantage of using the total percentage is that (in theory) the entire class can get an A. The second method uses normal (z) scores, which depend on the overall distribution of test scores. The advantage of using z-scores is that very good (or very bad) exam performances are more highly weighted. You can track your current grade status via your SS number using the Grade tracker .

    Regrading: Request for regrading of any material (exam or problem set) must be made in writing to the grader using a special form (available from Dr. Walsh or the grader) within 1 week of receiving the grade. The complete exam or problem set may be regraded, and a higher or lower score may result.

    Class policy on missed exams: Attendance is required for lecture and problem solving sessions. The Friday 2 p.m. meeting in 100 BSE is mandatory. Students will receive no credit, a zero, for problem sets and exams that are missed. NO MAKE UP EXAMS OR PROBLEM SETS WILL BE GIVEN.

    Procedure to Resolve Disputes: First see grader; then Dr. Walsh

    Class policy on study groups: You are encouraged to form study groups to discuss lecture material and problems sets. If you study and discuss problem sets in a study group put the names of all members of your study group on the first page of your answers. You will NOT be penalized for this. HOWEVER, DO NOT COPY ANSWERS FROM EACH OTHER. Discuss the problems in your study group and then go home and write up your answers alone.

    Class policy on "academic integrity": Your academic work (exams and problem sets) must be your own; do not copy answers to problem sets or anything else; cheating and plagiarism will not be tolerated on exams or problem sets. If you are caught, any combination of the following will occur (UA Code of Academic Integrity): a zero grade will be assigned for the work; course grade dropped one letter grade; course grade of F; disciplinary probation from University; suspension from the University; notation "Declared guilty of violation of the Code of Academic Integrity" put on student's permanent record.

    Honors

    Meeting time and place : Monday 2-3, BSW 212 (ROOM CHANGE)

    Honors handout (pdf file)

    Assignments

    1. Due Monday 13 Sept
    2. Due 18 October
    3. Due 1 November
    4. Due 8 November
    5. Due 22 November
    6. Due 29 November
    7. Due 6 December

    Instructors

    Exams

    Previous Exams