Lecture 5: Chromosomal Theory of Heredity

A review (along with self-test) can be found on the Cell biology page of the U of A biology project.

Walter Sutton (US grad student), Theodor Boveri (German Biologist) suggested that

Chromosomes contain the units of heredity

Why? Because Mendel's particles parallel the behavior of chromosomes at meiosis

• Showed independent assortment of chromosomes using observations of a heteromorphic chromosome pair (from a grasshopper) at anaphase

Studies strains of Jimsonweed


Strains of containing different extra chromosomes different in fruit appearance. 12 stains containing different extra chromosomes and 12 different appearances.

• Used red and white-eyed mutants in Drosophila, see pg. 68-70 (you will not be responsible for this reading, but it is interesting)
  

  X^R = red, X^r = white; Red dominant

  In females:

  X^R X^R , X^R X^r = red-eye female

  X^r X ^r = white-eyed females

  In males:

  X^R Y = red-eye male

  X^r Y = white-eyed male

  Lecture 6