Study Guide for 182 Exam 2
Disclaimer: Just because something is not mentioned here, don't assume it will be completely left off the exam!! This study guide highlights the key areas you should know, but don't make this your exclusive source for studying!!
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Be sure you can do problems along the lines of those in the two sample problem sets. Many of the problems on these problem sets are harder than those on the exam, so if you can do all of problems you are in good shape!
In particular, be sure that you know:
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how to compute allele frequencies from genotype frequencies
- Freq(A) = freq(AA) + (1/2)freq(All A- heterozygotes)
- how to compute genotype frequencies from allele frequency (Hardy- Weinberg)
- Freq(AA) = freq(A)2 ; Freq(Aa) = 2 freq(A) freq(a)
- how to use the formula for overdominant selection (if needed, it will be given)
- the definition of fitness and, given genotype fitnesses, which allele selection will fix.
- how to use parent and midparent-offspring regressions:
- slope parent-offspring = h2 /2
- slope midparent-offspring regression = h2
- (offspring mean - pop mean) = ( h2 /2) (parental value - pop mean)
- offspring mean - pop mean) = ( h2 ) (midparental value - pop mean)
- how to use sib information to compute h2
- corr(identical twins) = h2 + c2
- corr(non-identical twins) = h2 /2+ c2
- 2[ corr(identical twins) -corr(non identical twins) ] = h2
- for twins separated at birth, c2 = 0
- corr(identical twins) = h2 , corr(non-identical twins) = h2 /2
Know the geological time table. Anything on the handout is fair game.
Know the importance of major historical figures, their rough historical order, and their contributions. Names you should know include - Buffon
- Erasmus Darwin
- Lamarck
- Malthus
- Charles Darwin
- Lyell
- Hutton
- Wallace
- Galton
- Pearson
- Bateson
- Wright
- Fisher
- Haldane,
- Fleeming Jenkin
- Fox
- Kimura
- Oparin
- Miller
- Urey,
- Cech
Know the major evidence for evolution.
What are the key steps in the origin of life and the experimental models for some of these?
What is the neutral theory of molecular evolution?
What are some examples supporting a regulatory versus structural change model for the evolution of new gene functions?