182 Practice Problems: Quantitative Genetics
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since 26 Feb 1996 

If the slope of a parentoffspring regression is 0.25, what is the
heritability h^{2}?
 If the slope of a midparentoffspring regression is 0.75, what is the
heritability h^{2}?
 If h^{2} = 0.3, the population mean is 10, and the value of a parent is
15, what is the expected mean of an offspring from this parent?
 If h^{2} = 0.4, the population mean is 16, and the value of both parents
are mother = 12, father = 17.
 What is the midparental value?
 What is the expected mean of an offspring from these
parents?
 If the mean of a group of selected parents is 10 units above the population mean, while the mean value of their offspring is 3 units above the original population mean, what is the heritability h^{2}?
 Suppose 5 locus underlie a character of interest and that each capital letter allele at each locus adds value one to the character (so that genotype aabbccddee has value 0 while AABBCCDDEE has value 10). Suppose Freq(A) = Freq(B) = ... = Freq(E) and we assume HW for both parts a) & b).
 If Freq(A) = 0.7, what is the probability of an individual with genotype aabbccddee ?
 Suppose now that selection changes the allele frequencies to Freq(A) = 0.1, now what is the probability of an individual with genotype aabbccddee ?
 If the correlation between dizygotic twins for weight is 0.5, while the correlation between monozygotic twins is 0.75, what is the heritability of weight?
Solutions